Efficiency of Early Ureteric Stenting for Urosepsis Associated with Urinary Tract Lithiasis

Authors

  • Celso Marialva Serviço de Urologia, Hospital Garcia de Orta – Almada, Portugal
  • Alexandre Macedo Serviço de Urologia, Hospital Garcia de Orta – Almada, Portugal
  • Nuno Ramos Serviço de Urologia, Hospital Garcia de Orta – Almada, Portugal
  • Vanessa Metrogos Serviço de Urologia, Hospital Garcia de Orta – Almada, Portugal
  • Miguel Carvalho Serviço de Urologia, Hospital Garcia de Orta – Almada, Portugal

DOI:

https://doi.org/10.24915/aup.37.1-2.92

Keywords:

Urolithiasis, Sepsis, Ureteral catheterization

Abstract

Introduction: Our objective was to evaluate the differences between the early or delayed placement of the ureteral stent in patients with urosepsis associated with urinary tract lithiasis.

Material and Methods: Retrospective review of patients admitted to our institution between 2011 and 2015 with the diagnosis of urosepsis associated with urinary tract calculi, having ureteral stent placement. Early and delayed stenting groups were defined by the median waiting for ureteral stent placement. The primary outcomes were length of hospital stay (LOS) and spontaneous stone passage (SSP) after stent placement. Statistical analysis included chi-square test, linear regression and Spearman correlation.

Results: A total of 42 patients (mean age: 58; 32 females) had a mean number of 3.38 days since emergency room admission to ureteral stenting. The median wait to ureter stenting was 2.5 days. The overall mean length of hospital stay was 12.2 days. The early stenting group had a significantly shorter LOS than the delayed stenting group (mean 5.6 vs 18.8 days; p<0.001). The early stenting group had predominantly lumbar calculi compared to the delayed stenting group (76.2% vs 42.8%; p=0.029). The early stenting group had improved SSP compared to the delayed group (61.9% vs 47.6%; p=0.268). If we consider the lumbar calculi only, there is a relation in SSP between early and delayed stenting groups (p=0.027).

Conclusion: There is a significant reduction of LOS in patients with urosepsis associated with urinary tract lithiasis when early ureteral stenting is performed. We observed a trend of improved stone passage in the early stenting group with significance in lumbar calculi between the two groups.

Downloads

Download data is not yet available.

Author Biography

Celso Marialva, Serviço de Urologia, Hospital Garcia de Orta – Almada, Portugal

Urology Urology Resident

References

- Pallett A, Hand K.: Complicated urinary tract infections: practical solutions for the treatment of multiresistant Gram-negative bacteria. J Antimicrob Chemother 65: 25-33, 2010.

- Zachariah G., Oredein-McCoy, et al.: Emergent ureteric stent vs percutaneous nephrostomy for obstructive urolithiasis with sepsis: patterns of use and outcomes from a 15-year experience BJU International 112, E122–E128, 2013.

- Preminger GM, Tiselius HG, Assimos DG et al.: Guideline for the Management of Ureteral Calculi. Eur Urol 52: 1610–31, 2007.

– Nishiguchi S., Branch J., et al.: Effectiveness of Early Ureteric Stenting for Urosepsis Associated with Urinary Tract Calculi Intern Med 53: 2205-2210, 2014.

- Russo, P. Urologic emergencies in the cancer patient. Semin Oncol, 27: 284, 2000.

– Fernbach, S. K., Maizels, M. and Conway, J.: Ultrasound grading of hydronephrosis: introduction to the system used by the Society for Fetal Urology. Pediatr Radiol, 23: 478, 1993.

- Hyppolite, J. C., Daniels, I. D. and Friedman, E. A.: Obstructive uropathy in gynecologic malignancy. Detrimental effect of intraureteral stent placement and value of percutaneous nephrostomy. ASAIO J, 41: 318, 1995.

- Lau, M. W., Temperley, D. E., Mehta, S. et al.: Urinary tract obstruction and nephrostomy drainage in pelvic malignant disease. Br J Urol, 76: 565, 1995

- Yoshimura K, Utsunomiya N, Ichioka K, Ueda N, Matsui Y, Terai A.: Emergency drainage for urosepsis associated with upper urinary tract calculi. J Urol 173: 458-462, 2005.

- Yamamoto Y, Fujita K, Nakazawa S, et al. Clinical characteristics and risk factors for septic shock in patients receiving emergency drainage for acute pyelonephritis with upper urinary tract calculi. BMC Urol 12: 4, 2012.

- Arakaki Y. Emergency urological disease. Kyukyuigaku (Emergency Medicine) 34: 199-205, 2010.

Published

2020-07-17